Palo Alto Networks’ recent State of Cloud Report, released in December 2025, reveals that customers are significantly expanding their use of cloud infrastructure to support new AI solutions, applications and services. The report also notes that 99% of respondents suffered at least one attack against their AI infrastructure in the last year.

As enterprises accelerate the adoption of agentic AI and cloud computing, Palo Alto Networks and Google Cloud have announced the expansion of their strategic alliance to enable the secure development and deployment of AI solutions and provide a foundation of trust that helps organizations realize the full potential of AI with confidence and security.

The collaboration combines Google Cloud’s leading AI and infrastructure capabilities with Prisma AIRS, Palo Alto Networks’ comprehensive AI security platform, to protect the next generation of digital business through solutions designed for complex, highly distributed environments.

Security at all layers

The agreement aims to address these challenges through a strengthened commercial strategy and the integration of security in all layers of the hybrid multicloud infrastructure, in each phase of application development and in all endpoints. All of this will allow companies to innovate with the most advanced AI capabilities, relying on security solutions that protect their intellectual property and data in the cloud.

What this new alliance offers

  • End-to-end AI security, from code to cloud

Customers will be able to protect AI workloads and data in production on Google Cloud, including Vertex AI and Agent Engine, with Prisma AIRS from Palo Alto Networks. Additionally, by securing key developer tools like the Agent Development Kit (ADK) with Prisma AIRS, this expanded collaboration ensures a secure foundation for the next generation of AI applications built on Google Cloud. This includes AI Posture Management for visibility, AI Runtime Security™ for real-time defense, AI Agent Security for autonomous systems, AI Red Teaming for proactive testing, and AI Model Security for vulnerability analysis, all integrated into advanced protection solutions.

  • Next-generation software firewall (SWFW) powered by AI

Palo Alto Networks VM-Series firewalls are designed to protect cloud (public, private and hybrid) and virtualized environments, providing deep packet inspection and threat prevention in a software format. Advanced integrations with Google Cloud will now enable customers to maintain strong security policies and accelerate Google Cloud adoption with flexible and scalable solutions.

  • AI-powered secure access service edge (SASE) platform

Palo Alto Networks’ Prisma SASE is a cloud platform that protects access and connectivity for remote users, branch offices, and mobile devices, along with deeper integration of security solutions into native Google Cloud AI services. Palo Alto Networks’ Prisma Access runs on top of Google’s network, improving the user experience when accessing cloud and AI applications running on Google Cloud, while leveraging Google Cloud Interconnect to help customers connect their WAN infrastructure across multiple clouds and applications and maintain consistent security policies.

  • Simplified and unified security experience

The close alignment between both companies ensures that customer solutions are pre-validated and designed to work together, eliminating integration challenges and operational friction that can slow down security teams. This allows customers to deploy protection more quickly, simplify regulatory compliance, and gain a single, comprehensive view of security across their hybrid multicloud environment.

According to BJ Jenkins, president of Palo Alto Networks: “Every board is asking how to harness the potential of AI without exposing the business to new threats. This alliance answers that question. We are removing the friction between security and development, and offering a unified platform where the most advanced security is natively part of the process of creating what comes next. Together with Google, we are deeply integrating our AI-powered security into the very fabric of Google Cloud, turning the platform itself into a proactive defense system.

For Matt Renner, president and chief revenue officer of Google Cloud: “More and more companies are turning to Google Cloud and Palo Alto Networks to protect their applications and data, together and without friction. This latest expansion of our alliance will ensure that our joint customers have access to the right solutions to protect their most critical AI infrastructure and develop new AI agents with security built in from the start.”

Performance, scalability and reliability

Building on a track record of success that includes more than 75 joint integrations and $2 billion in sales through the Google Cloud Marketplace, Palo Alto Networks is also expanding its commitment to running its security platforms on Google Cloud’s secure and trusted AI infrastructure by migrating key internal workloads to Google Cloud under a new multi-billion-dollar, multi-year agreement.

Additionally, Palo Alto Networks now uses Google Cloud’s Vertex AI platform and Gemini Language Models (LLM) to power its copilots. Together, these initiatives strengthen engineering collaboration and ensure that customers running Palo Alto Networks on Google Cloud benefit from solutions that are natively optimized for performance, scalability, and reliability.